Liquid Dosage
Monoclonal Antibodies
GEA is a leading specialist in the field of process equipment for liquid processing and metering for the pharmaceutical and biotech industries, including fermentation plant for the manufacture of products such as monoclonal antibodies (mAbs) for diagnostic and therapeutic purposes.
Monoclonal antibodies are known as targeted therapies because they work by targeting specific proteins on the surface of cells. Successfully used to treat cancers, tumors and other serious diseases, mAbs are — compared with other biopharmaceutical products — large proteins that require relatively high administration doses and traditionally necessitate high-volume manufacturing equipment/systems and facilities. GEA offers production systems for monoclonal antibodies that are produced in state-of-the-art stainless steel bioreactors by specific cell cultures.
From Culture to Harvest
The cell culture process is done in several steps, starting with 10 L precultures and successively cultivating intermediate batches up to a final production volume of up to 20,000 L. These systems comprise the vessel, with the stirrer as the core element, and peripherals such as temperature control systems, clean-in-place (CIP) components, aeration and deaeration systems, input systems and automated sensors, actuators and the operator interface.
Support processes, such as media preparation and harvest systems are also available from GEA. The process integration of separators and filters for the harvest step is also within GEA’s scope of service. Because of the high sensitivity of the cells and the need for operator and product safety, all GEA system components are designed according to the latest standards and have the highest grade of finish quality.
Products & Technologies
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Aseptic valves & components
Aseptic valves face exceptionally high demands within UltraClean and Aseptic processes. You can be assured that they all provide highest quality in terms of hygienic design and sustainability.
Centrifugal Separator
GEA separators are designed for liquid-based applications. Using centrifugal force, they are used for separating suspensions consisting of two or more phases of different densities, i.e. they can be used for liquid-liquid separation, for liquid-liquid-solid separation or for liquid-solid separation. They are equally as effective at separating liq...
CIP/SIP Solutions
Innovative CIP concepts of GEA meet comprehensive high standards. Our experts guarantee product safety at every point of the process. Every upgrade is adapted to individual local conditions and customer requirements and leads to noticeable savings.
Hygienic pumps
GEA Hilge offers a versatile range of centrifugal and positive displacement pumps for a wide variety of sensitive applications in the beverage, food and pharmaceutical industries.
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GEA Insights
Shifts in food packaging: 4 trends
Thermoforming has long played a central role in food packaging. Now it is facing a major shift. As regulations tighten, materials evolve and costs rise, form fill seal lines must do more than run reliably – they now shape how food stays fresh, affordable and recyclable. Take a look at the key thermoforming trends informing the food packaging and delivery landscape.
Fruit storage at Betko: Control from peak harvest to global delivery
From the orchards of the Cape to store shelves across 40 countries, the South African packhouse Betko has built a business on freshness, timing and reliability. With GEA’s controlled atmosphere refrigeration technology, the company can now store apples and pears for up to 14 months and cut energy consumption by 20%, with a partnership of more than 30 years at the heart of it all.
