Liquid Dosage
Insulin
With diabetes on the rise and the global insulin market estimated to be worth more than $32 billion by 2018, demand for GEA technologies for the production of this life-saving drug is already high and set to increase, particularly in new markets and emerging economies.
State-of-the-Art Solutions
GEA produces and supplies process systems for the production of liquid products for the pharmaceutical and biotechnological industries, and has a proven history of successfully installing plant for the production of insulin, including the engineering, delivery, commissioning and qualification of entire ultra-pure media systems as well as various process equipment and cleaning installations.
A worldwide technology leader in insulin production, GEA is able to supply the clean utility systems and manage the integration of all the main processes, including fermentation, harvesting, chromatography, filtration and freeze drying.
From Fermentation to Freeze Drying
The biosynthetic production of human insulin is done using bacteria or yeast cells. Following fermentation, or the conversion of chemical raw materials by micro-organisms, the biomass is extracted using a nozzle separator, washed, concentrated and finally precipitated to produce insulin crystals.
Centrifuges and process lines provided by GEA have an established pedigree in the clarification, separation, classification, concentration and fractionation steps. Nozzle separators also play an important part in the production process. Further, GEA chamber or self-cleaning separators can be used in the subsequent crystallization stages.
GEA is a single-source supplier of a variety of fermenters, media preparation, buffer storage, harvesting and cell rupture solutions, equipment for the purification and isolation of cells, separation (after both first and final crystallization), the production and distribution of WFI, CIP and freeze drying technologies, all of which can be installed and integrated into a state-of-the-art insulin production facility.
Producten & technologieën
Weergegeven 4 van 14
Aseptic valves & components
Aseptic valves face exceptionally high demands within UltraClean and Aseptic processes. You can be assured that they all provide highest quality in terms of hygienic design and sustainability.
Centrifugaalseparator
Separatoren van GEA zijn ontworpen voor toepassingen met vloeistof. Met behulp van centrifugaalkracht kunnen ze worden gebruikt voor het scheiden van suspensies die twee of meer fasen met verschillende dichtheden bevatten; dat wil zeggen dat ze gebruikt kunnen worden voor vloeistof-vloeistof-scheiding, vloeistof-vloeistof-vastestof-scheiding of v...
CIP/SIP-oplossingen
Innovatieve CIP-concepten van GEA voldoen aan hoge normeringen. Onze experts garanderen productveiligheid in elke fase van het proces. Elke upgrade wordt aangepast aan individuele plaatselijke situaties en eisen van de klant, en leidt tot aanzienlijke besparingen.
Compressieblok homogenisator
Compressieblokken van GEA vormen de pulserende kern van homogenisators, omdat ze het homogenisatieproces activeren door het product bij hoge druk door het homogenisatieventiel te pompen.
Downloads
GEA-inzichten
Modern herd management: a smarter way to farm
In a dairy herd, every cow has her own story – and modern herd management tools help tell it. By tracking health, habits and needs, these smart systems let farmers care better, work smarter and keep milk flowing. It's the secret behind happy herds and successful, more sustainable dairy farming.
De toekomst voeden: de kracht van vriesdrooginnovaties
Afvalreductie is belangrijk voor ons bij GEA en door de kracht van vriesdroogtechnologie te benutten, kunnen we voedseloverschotten omzetten in waardevolle, duurzame producten die ons helpen afval te reduceren, de houdbaarheid te verlengen en een beter bestendige voedselvoorzieningsketen voor toekomstige generaties te creëren.
