ConsiGma®
ConsiGma® Granulation and Drying (GD) Modules
Based on proven continuous twin-screw granulation technology, the ConsiGma® GD modules enable the production of higher quality granules under better control, even in a bin-2-bin set-up.
Available in 3 standard sizes, depending on the desired throughput (from 5 to 120 kg/h, to be verified by testing), the systems can be customized with a number of options to suit customer needs.
Ideal for pharmaceutical companies who wish to benefit from higher levels of process control and better-quality product but prefer to maintain their current mode of operation.
The Conductor software ensures seamless control of the entire process, full reporting and tracking of OOS. Material genealogy can be integrated into the controls. Handshaking with up- or downstream equipment can also be offered.
Standard Configuration
- 1 loss-in-weight feeder (to be loaded with pre-mix from an IBC)
- Twin screw granulator
- Segmented fluid bed dryer
- Granule conditioning unit
Available Options
- Choice of feeder (GEA or qualified third-party feeder)
- Pressure Shock Resistant (PSR) design
- Suitable for Solvents processing
- Lighthouse Probe® for LOD measurement
- Second HMI
- Material genealogy
- Material handling system including containment features
Main Benefits
- Controlled granulation
- Small amount of at-risk API
- Replace only a single step in the process with minimal impact as per SUPAC guidelines; plant scheduling and testing remain the same as with current process
- More equal granulation binder distribution
- High flexibility from very low to very high API content
- Porosity control of the granules
- Control of granule particle size distribution
- Use of solvent-free binders
- Compatible with variable throughput capacities
Read more about how GEA and its partners are implementing this technology to lead the way toward smaller, more flexible, continuous processing technologies that are transforming the future of pharmaceutical development and manufacturing.
Downloads
Prodotti correlati
ConsiGma® Direct Compression with Linear Blending (DC-LB) Lines
A highly integrated solution for continuous linear blending and direct compression, the ConsiGma® DC-LB lines offer all the advantages of continuous manufacturing: supply chain agility, small footprint, controlled blending and compression and improved quality.
ConsiGma® Gentle Coater
The ConsiGma® Gentle Coater is based on the GEA high-performance tablet coating technology that gently and accurately deposits controlled amounts of coating materials onto tablet cores — even if they are hygroscopic or friable.
ConsiGma® Granulation and Compression (GC) Lines
Highly integrated solutions for continuous wet granulation, drying and tablet compression, the ConsiGma® GC lines offer all the advantages of continuous manufacturing: supply chain agility, small footprint, controlled granulation and improved quality.
ConsiGma® 1 - R&D Granulation and Drying
The ConsiGma® 1 offers standalone continuous twin-screw granulation and drying for small-scale R&D operations. It allows users to develop the process and achieve high granule quality on a compact unit.
Approfondimenti GEA
Kytero 10 I grandi cambiamenti iniziano in piccolo
Con GEA kytero 10, i ricercatori e gli sviluppatori dei settori biofarmaceutico, alimentare e New Food hanno ora a disposizione un potente acceleratore di ultima generazione.
Fueling the circular economy in shipping
Ports now compete not just on logistics, but on sustainability. At Greece’s Piraeus port, an advanced processing and recovery facility recycles ship waste oil into fuel. Equipped with GEA’s high-performance centrifuges, it sets a new benchmark for state-of-the-art, environmentally responsible port operations.
Uova più sostenibili sulle nostre tavole
GEA aiuta i clienti a testare e sviluppare prodotti e ingredienti alternativi alle uova realizzati con la fermentazione di precisione.
