At GEA, we believe that continuous processing improves the quality of pharmaceutical end products: by focusing on quality during the whole product lifecycle, not just “tested in” quality; and by understanding the capability of your processes, managing sources of variability and decreasing any associated risks.
Our solution for continuous drying and particle processing plants is ConsiGma®, a 6 sigma-inspired manufacturing platform, incorporating different technologies to produce oral solid dosage forms in a continuous, cost-efficient way:
- by collecting more information during R&D phase, in a short time with less product
- by excluding risky, time- and product consuming scale-up exercises
- by introducing online measurement and closed loop control targeting real-time release (6 sigma production)
- by incorporating flexible batch size (JIT production), reducing inventory
- by reducing the energy cost per tablet, reducing environmental impact.
Products
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ConsiGma® 1 - R&D Granulation and Drying
The ConsiGma® 1 offers standalone continuous twin-screw granulation and drying for small-scale R&D operations. It allows users to develop the process and achieve high granule quality on a compact unit.
ConsiGma® Conductor
An indispensable part of the ConsiGma portfolio, the Conductor control system architecture ensures smooth operation and communication between the different elements of a pharmaceutical continuous manufacturing line
ConsiGma® Direct Compression with Linear Blending (DC-LB) Lines
A highly integrated solution for continuous linear blending and direct compression, the ConsiGma® DC-LB lines offer all the advantages of continuous manufacturing: supply chain agility, small footprint, controlled blending and compression and improved quality.
ConsiGma® Direct Compression with Ribbon Blending (DC-RB) Lines
A cost-effective solution for continuous dry blending and tablet compression using ribbon blending, ConsiGma® DC-RB lines make the advantages of continuous manufacturing (supply chain agility, small footprint and improved quality) available for all.
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Approfondimenti GEA
L'equazione dell'acqua
In tutta Europa, la siccità è una realtà ricorrente – e non è più limitata al sud. Sebbene la disponibilità idrica influenzi sempre più la scelta della sede delle industrie, il suo valore è determinato dal contesto locale. Esistono molte soluzioni tecnologiche per garantire l'efficienza idrica nei processi industriali, ma anche l'ubicazione, il fabbisogno energetico e altri fattori rivestono un ruolo fondamentale.
