Liquid Dosage

Liposomes

As a drug delivery system, liposomes offer significant therapeutic benefits in terms of active ingredient targeting and controlled release. Hydrophobic moieties can be dissolved into the liposome membrane — a lipid bilayer — and, as such, they can be used to carry both hydrophobic and hydrophilic molecules.

To deliver molecules to sites of action, the liposome binds and fuses with other bilayers, such as a cell membrane, thus delivering its contents. By making liposomes in a drug solution (which would not normally be able to penetrate the membrane), they can be (indiscriminately) delivered through the lipid bilayer into the cell interior.

High-pressure homogenization is an ideal liposome production method, offering excellent results in terms of reduced vesicle diameters. Further, a wide range of different sizes and distributions can be achieved by altering the applied pressure and the number of passes through the homogenizer. 

A wide range of products, including liposomes, can be freeze dried to retain their original properties. By adding water or other solvents, they can be reconstituted easily and very quickly to a usable solution. There is no need for cooling during storage, which is both cost-effective and makes handling easier. 

GEA specializes in the design and manufacture of freeze dryers for the pharmaceutical and biotech industries and has an in-depth knowledge of lyophilization technology.

Approfondimenti GEA

Lemgo plant building

Past and future merge in Lemgo's pioneering district heating project

Theo van der Zwaag from the Netherlands stands in front of a GEA automated feeding robot.

Le soluzioni GEA consentono di ottenere prodotti lattiero-caseari di origine non...

CIAL Chile Employees stand in front of a line of defrosters from GEA.

La tecnologia di separazione GEA compie 130 anni

Ricevi notizie da GEA

Resta in contatto con le innovazioni e le storie GEA iscrivendoti alle news di GEA.

Contattaci

Siamo qui per aiutarti! Solo pochi dettagli e saremo in grado di rispondere alla tua richiesta.