Liquid Dosage
Hormones & Steroids
Steroids, endogenous hormones such as the sex hormones estrogen and testosterone or the hormones of the adrenal cortex, cortisol and aldosterone, play a key role in metabolic processes and have a number of pharmaceutical applications, including hormone therapy, anti-rheumatic, anti-arthritic and bodybuilding preparations.
Mainly used in the global hormone replacement therapy, currently worth about $3.6 billion, the three major segments comprise estrogen, growth and thyroid hormone, and testosterone replacement therapy. A major market driver is the increased awareness of postmenopausal hazards amongst women; others include an ageing population, innovative drug delivery systems and the pharmerging economies.
Predominantly based on cholesterol, steroid hormones are synthesized in the endocrine glands and transported to target tissue by the blood. At their site of action, they dock with highly specific cellular receptors and perform a key function in protein formation. To produce steroid hormones for pharmaceutical applications outside the body, a direct extraction procedure from special nutrient solutions is used.
Counter-Current Liquid-Liquid Extraction
In continuous direct extraction from GEA, the fermented nutrient solution is treated by liquid-liquid extraction in a counter-current process. Following precipitation, concentration, crystallization and drying of the extract, the steroid hormones are available in the form of a raw salt and can be correspondingly processed by the pharmaceutical industry. In a continuous direct extraction process, the fermented nutrient solution undergoes a counter-current liquid-liquid extraction process (also known as also known as solvent extraction or partitioning). Following precipitation, concentration, crystallization and drying, the extracted steroid hormones are available in the form of a raw salt and can be subsequently processed by the pharmaceutical industry.
Fromfacility design and layout, manufacturing process controls (including adherence to standard operating procedures) and environmental control systems (HVAC) to extraction systems, industrial hygiene solutions and fully integrated, end-to-end containment solutions, GEA has the experience and know-how to implement and optimize end-to-end production lines for steroid- and hormone-based applications.
Продукты и технологии
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Aseptic valves & components
Aseptic valves face exceptionally high demands within UltraClean and Aseptic processes. You can be assured that they all provide highest quality in terms of hygienic design and sustainability.
Hygienic pumps
GEA Hilge offers a versatile range of centrifugal and positive displacement pumps for a wide variety of sensitive applications in the beverage, food and pharmaceutical industries.
Lyophilizers (Pharma Freeze Dryers)
GEA's thorough understanding of the lyophilization process enables them to supply a comprehensive range of products and services, comprising laboratory equipment, pilot plants for research and small-scale production batches, industrial size pharmaceutical production freeze dryers.
R&D Drying Systems
GEA's versatile range of R&D drying & particle processing equipment - for advanced powder processing within food and dairy products, chemicals and pharmaceuticals.
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Аналитика GEA
Kytero 10 — большое начинается с малого
GEA kytero 10 — это мощный ускоритель последнего поколения для исследователей и разработчиков в области биофармацевтики, пищевой промышленности и производства новых продуктов питания.
Как доильный робот изменил жизнь мамы
Жизнь Мишель Шнайдер (Michele Schneider) приняла неожиданный оборот, когда она вышла замуж за Вирлея (Virlei), начинающего молочного фермера, и они вдвоем открыли молочное хозяйство Fazenda Inovação Schneider Milk в Бразилии. Мишель никогда ранее не работала на молочной ферме, но несмотря на это животные и работа на ферме быстро стали ее настоящим призванием. Но при этом у нее вырос и объем работы.
В меню: яйца, полученные отвечающим принципам устойчивого развития методом
GEA помогает клиентам тестировать и масштабировать производство альтернативных яичных продуктов и ингредиентов, изготовляемых методом прецизионной ферментации.
