Manufacturing Antibiotics and Anti-Infectives
Antibiotics, compounds or substances that combat bacterial infections and kill or slow down their growth, comprise one of the most important groups of drugs in the fight against infectious diseases. Representing approximately 13% of total pharmaceutical consumption, they have the highest market share of any pharmaceutical product.
Currently, owing to increased consumption in low- and middle-income countries (LMICs) and the rising prevalence of infectious diseases, there is a growing demand for antibiotics such as beta lactam and beta lactamase inhibitors.
The discovery of advanced prospect molecules and novel combination therapies to treat antibiotic-resistant microbial infections are expected to offer significant — and profitable — opportunities for many market players. Driven by new product innovations, high levels of R&D investment and the pharmaceutical industry’s need to ameliorate the issue of resistance, the antibiotic market is expected to show continued growth.
Producing these products can pose several challenges. For example, some may require contained handling to prevent potentially life-threatening allergic reactions. Others are pH-sensitive and may be best administered in the form of effervescent preparations.
From R&D-scale and standalone manufacturing equipment to completely integrated process lines that maximize operational reliability, GEA supplies a comprehensive range of equipment and solutions for the industrial-scale production of antibiotics, antibacterials and anti-infectives.
Including high shear mixers, fluid bed dryers, single pot systems, extruders and spheronizers, blenders and containment solutions, right through to tablet compression and aseptic spray drying systems, we provide the pharmaceutical industry with high quality, cost-effective, integrated modules, systems and complete lines for the production of dry sterile dosage forms.
GEA can help you to choose the most suitable equipment, assessing each project on its individual needs and tailor the process to match your specific requirements.
Products & Technologies
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Analytical, in-line control & measurement devices
Combining process monitoring using online analyzers, together with solid process engineering principles and advanced process modelling techniques will enable processes to be actively controlled in order to compensate for input variations.
CIP/SIP Solutions
Innovative CIP concepts of GEA meet comprehensive high standards. Our experts guarantee product safety at every point of the process. Every upgrade is adapted to individual local conditions and customer requirements and leads to noticeable savings.
Contained Materials Handling Systems
Contained Materials Handling solutions for Primary and Secondary Pharmaceuticals and Healthcare. With extensive experience within the generics sector, supply a wide range of technologies and equipment that improve and enhance the efficiency and performance of Oral Solid Dosage production.
Continuous Direct Compression Line
The ConsiGma® DC for direct compression is the latest expansion of GEA's continuous portfolio for cost effective, compact, high yield manufacturing systems. It offers a robust and flexible manufacturing method for a wide range of products.
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GEA Insights
The breakthrough that changed spray drying
In 1976, NIRO engineers responded to a competitive challenge by rethinking what spray drying could do. Their idea became the multi-stage dryer MSD. Fifty years later, the same fundamental principle helps turn liquids into the powders used in essential nutrition products and important medicines around the world. Refined through decades of engineering expertise, customer insight and continuous development, MSD is a story of innovation with lasting impact.
Beyond the machine: unlocking better plant performance
An efficient machine does not automatically make an efficient factory. Real improvement often starts by looking beyond individual equipment and understanding how processes, energy systems and operating decisions affect one another. It’s a holistic approach designed to uncover opportunities that might otherwise be missed.
How a valve reshapes the way food and drinks are made
In food and beverage plants, valves are commonly operated using compressed air. GEA Hydract® Actuation Technology moves valves with water instead, in a closed, digitally controlled circuit. The result is a valve that can be held exactly in place and steered in fine-tuned steps. This results in lower energy use and greater control.
