Liquid Dosage

Blood Plasma Fractionation

The processing of blood into its various components must meet the very highest requirements to ensure clinical excellence. Because of the inherent variability of the source material and the absolute need for product purity, the demands placed on systems used to manufacture blood- and plasma-derived products are huge. Gentle process conditions and high quality equipment are essential.

The GEA Advantage

A specialist in this field, GEA uses its experience and expertise to unite a range of technologies to create complete processing plants for blood plasma processing, including controlled precipitation, centrifugation and filtration for solid/liquid separation, thermal and chemical inactivation, ultrafiltration/diafiltration, nanofiltration and chromatography. The company has successfully planned and built plants for blood plasma fractionation all over the world.

GEA supplies plant and components for fractionation, concentration, pre- and post-virus inactivation, purification and buffer production, storage and distribution. As well as being an aseptic process, blood plasma fractionation involves precise cooling of the separation vessel at various stages, requiring highly accurate control systems. Depending on the application, plasma may need to be frozen to –30 °C within 60 minutes. GEA can supply equipment to accurately maintain such extremely low temperatures.

An essential part of high-quality blood plasma production is an integrated CIP/SIP system. GEA provides efficient cleaning and sterilization processes to meet your individual demands and to ensure that sterile media is delivered to the right place at the right time. We offer a wide range of cleaning options, from mobile, independent cleaning systems up to diverse CIP satellites fed with conditioned cleaning solutions.

High Standards, High Quality

In addition, the process must comply with a large number of national and international standards and statutory provisions. Manufacturers expect great precision in the manufacture and assembly of their process plant; every detail of the design must comply with the highest standards to avoid production errors. Using high-performance processing equipment from GEA helps to guarantee reliable production.

Whatever you need your process plant for — from the fractionation and manufacture of products such as immunoglobulins or human albumins to Factor VIII/Factor IX — our wide range of plant concepts will provide for any task to be performed in a safe and cost-effective way and take account of any specific requirements or conditions.

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