Liquid Dosage
Liposomes
As a drug delivery system, liposomes offer significant therapeutic benefits in terms of active ingredient targeting and controlled release. Hydrophobic moieties can be dissolved into the liposome membrane — a lipid bilayer — and, as such, they can be used to carry both hydrophobic and hydrophilic molecules.
To deliver molecules to sites of action, the liposome binds and fuses with other bilayers, such as a cell membrane, thus delivering its contents. By making liposomes in a drug solution (which would not normally be able to penetrate the membrane), they can be (indiscriminately) delivered through the lipid bilayer into the cell interior.
High-pressure homogenization is an ideal liposome production method, offering excellent results in terms of reduced vesicle diameters. Further, a wide range of different sizes and distributions can be achieved by altering the applied pressure and the number of passes through the homogenizer.
A wide range of products, including liposomes, can be freeze dried to retain their original properties. By adding water or other solvents, they can be reconstituted easily and very quickly to a usable solution. There is no need for cooling during storage, which is both cost-effective and makes handling easier.
GEA specializes in the design and manufacture of freeze dryers for the pharmaceutical and biotech industries and has an in-depth knowledge of lyophilization technology.
Products & Technologies
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Aseptic valves & components
Aseptic valves face exceptionally high demands within UltraClean and Aseptic processes. You can be assured that they all provide highest quality in terms of hygienic design and sustainability.
Centrifugal Separator
GEA separators are designed for liquid-based applications. Using centrifugal force, they are used for separating suspensions consisting of two or more phases of different densities, i.e. they can be used for liquid-liquid separation, for liquid-liquid-solid separation or for liquid-solid separation. They are equally as effective at separating liq...
CIP/SIP Solutions
Innovative CIP concepts of GEA meet comprehensive high standards. Our experts guarantee product safety at every point of the process. Every upgrade is adapted to individual local conditions and customer requirements and leads to noticeable savings.
Homogenizer Compression Block
GEA compression heads are the homogenizer pulsing core since they activate the homogenization process pumping the product at high pressure until it flows inside the homogenizing valve.
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GEA Insights
Heat pumps fast-track district heating decarbonization
The impact of global warming is increasingly apparent all over the world. Towns and cities everywhere face the same challenge: providing their communities with reliable, affordable, sustainably sourced heat. GEA spoke with an expert in the field, Kenneth Hoffmann, Manager, Heat Pumps at GEA Heating & Refrigeration Technologies, about tackling global warming faster.
Living the digital future of dairy farming with GEA
Something caught Farmer Tom's eye. Instead of another product demo, GEA showcased innovations via AR. That's only the start of GEA's interactive digital farm.
GEA homogenizers power bioinks for regenerative medicine
GEA scientists are working with researchers at the Graz University of Technology to configure a homogenization process and technology that turns eucalyptus pulp into 3D-printed, organic structures mimicking human veins, arteries and other tissues.
