Liquid Dosage
Therapeutical Proteins
Protein-based therapeutics are increasingly being developed as new chemical entities in the pharmaceutical and life science industries. Unlike small molecules, which are typically synthesized using chemical processes, most proteins need to be processed in living systems, mostly by recombinant DNA technology. The proteins can then be produced in their functional form (quaternary structure), rather than by microbial biosynthesis (bacteria/yeast), substantially reducing the downstream stages of the process.
The GEA Advantage
As the demand for large-volume products increases, so does the requirement for higher capacity reactors (up to 20,000 L) to realize economies of scale. GEA has responded to the changing needs of biopharmaceutical manufacturers and developed improved technology solutions to optimize both upstream and, with increasing titers, downstream processing, in terms of time and cost efficiency.
Based on its history of innovation and process development, GEA has a thorough working knowledge of therapeutic protein production and has used this competence to design better media and feeding strategies, optimize the fermentation stage and enhance physicochemical conditions during the manufacturing process.
A leading international supplier of integrated process systems, our extensive portfolio of products, technologies and services includes standard and customized fermenters, separators and entire production lines, as well as plant for the production, storage and distribution of clean utilities. Systems for the preparation of media, fluid management, cell cultivation and purification are also part of our global scope of supply.
As a competent manufacturer of complete plant for the life science industries, GEA is a full-service provider of solutions that meet your exact requirements and specifications. From planning, development and installation to qualification and maintenance, our experienced engineers will collaborate with your project team to supply innovative and efficient process solutions for your applications.
Products & Technologies
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Aseptic valves & components
Aseptic valves face exceptionally high demands within UltraClean and Aseptic processes. You can be assured that they all provide highest quality in terms of hygienic design and sustainability.
Centrifugal Separator
GEA separators are designed for liquid-based applications. Using centrifugal force, they are used for separating suspensions consisting of two or more phases of different densities, i.e. they can be used for liquid-liquid separation, for liquid-liquid-solid separation or for liquid-solid separation. They are equally as effective at separating liq...
CIP/SIP Solutions
Innovative CIP concepts of GEA meet comprehensive high standards. Our experts guarantee product safety at every point of the process. Every upgrade is adapted to individual local conditions and customer requirements and leads to noticeable savings.
Homogenizer Compression Block
GEA compression heads are the homogenizer pulsing core since they activate the homogenization process pumping the product at high pressure until it flows inside the homogenizing valve.
Downloads
GEA Insights
Beyond the firewall: Securing what matters at GEA
Companies like GEA process and store large amounts of sensitive data. However, security incidents, from ransomware attacks to physical intrusions and industrial espionage, are ever-expanding. GEA’s effective protection of its business partners’ data – as well as its own proprietary information – is evolving into a competitive advantage. We spoke with Iskro Mollov, GEA’s Chief Information Security Officer, about what it takes to protect a global business in a volatile world.
Smart, stylish, circular: polycotton recycling with Circ
Resource-efficient fashion has been a long-sought ambition amid the fashion industry’s considerable contributions to global carbon emissions. The need to close the loop by recycling textile fibers into virgin-like materials is higher than ever but seemed like a distant dream until now: Circ, GEA’s American customer and pioneer in the field of textile recycling, might be rewriting the future of the fashion industry.
New food tipping point
Alternative proteins are promising – yet still expensive to produce. The usual response is that scaling up will solve this issue. But what if the solution was really about getting better, not just bigger? From more efficient, high-yield processes to upcycling waste heat, engineers are reshaping how we grow food.
