Menü

Integrated Granulation Processing

Entegre Granülatörler & Kurutucular

GEA is uniquely qualified to provide integrated pharmaceutical process lines. Drawing on its world-class expertise and technologies, we offer an entire range of state-of-the-art process equipment that has been designed and built with system integration in mind.

Entegre Muhafaza Teknolojisi web

Integrated by Design

A modular approach allows customers to select standard process modules to suit specific project needs: fully integrated turnkey installations can be supplied, including fluid bed process equipment combined with top- and bottom-drive high shear mixer-granulators with integrated contained materials handling, wet and dry milling facilities, product handling systems, binder and coating preparation units, filtration units and tablet compression machines.

Safety, containment, product flow and building requirements are in-built for full integration and optimum process efficiency. Our service includes design, installation assistance, commissioning and process validation, as well as training and technical support. Installation, operation qualification and documentation are done according to FDA/GAMP guidelines.

Controlling Your Process

Advanced PLC-based automation provides seamless integration of process and CIP control functions. Options include a graphical MMI operator interface, online monitoring and trending, recipe handling, batch management, barcoding and full CIM integration. Industry standard communication networks ensure full compatibility with existing control strategies and plant-wide supervisory systems.

Process Analytical Technology

The FDA’s PAT (Process Analytical Technology) initiative has enabled GEA to combine its equipment design skills and process engineering know-how to integrate online (PAT) analyzers into its systems in a way that can provide real insight into the operation of the process and help customers to achieve key product quality targets. 

The goal of the PAT initiative is to ensure that pharmaceutical products are manufactured using processes that are understood and monitored so that the key quality characteristics of the products can be actively controlled.

Containment

Our distinctive specialization lies in the integration of the BUCK® containment technology into complete solutions for pharmaceutical solid dosage form facilities. With an emphasis on quality and GMP standards, we are committed to working together with our customers to deliver custom-built, first class solutions for projects of all sizes and complexity.

Safety and the Environment

For full compliance with national, local and in-house regulations, GEA offers a range of emission control options including solvent recovery systems, outlet filters and full containment plants. Equipment can be supplied to meet explosion-proof and pressure shock standards as required.

Cleaning and Maintenance

Katı Madde Dozajı için CIP Skid Ünitesi

Process optimisation depends on efficient, effective cleaning. Automation of the cleaning process ensures repeatability, allows validation and minimizes downtime. In recognition of the fundamental role played in today’s advanced powder processing industry by automated clean-in-place procedures, GEA has developed a unique approach to CIP.

Concealed services: The integrated design ensures that all lines and hoses for the utilities of the plant (water, electricity, hydraulics, etc.) are concealed. This creates a safe and uncluttered working space.

CIP and WIP systems: More efficient cleaning is one of the key advantages of system integration. We provide validated cleaning with minimal downtime. GEA offers CIP-by-design (patented) features into all of its process. Every aspect of the integrated plant, from inlet to discharge, has been value-engineered for optimum cleanability. Spray system, tanks cleaners, nozzles and seals are an integral part of our equipment design. Every plant delivered by GEA has a tailor made WIP or CIP system that suits your process.

İlgili Ürünler

Farmasötiklerin Akışkan Yataklı İşlenmesi

Farmasötiklerin Akışkan Yataklı İşlenmesi

GEA, farmasötik endüstrisine karıştırma, granülasyon, kurutma, peletleme ve kaplama için akışkan yataklı işleyiciler (ABD'de akışkan yataklı Multi-Processor™ olarak da bilinmektedir) temin etmektedir.

Gral™ Yüksek Parçalayıcı Granülatörler

Gral™ Yüksek Parçalayıcı Granülatörler

Whether the customer’s requirement is for high shear mixing or granulation, GEA has a solution for every processing challenge and can help select the technology that is most suitable for your Pharma application.

İlaç Üretim Tesisleri için CIP

İlaç Üretim Tesisleri için CIP

Proses optimizasyonu etkili ve etkin temizliğe bağlıdır. CIP sistemleri, kurutucular, yüksek-parçalayıcı granülatörler ve sıvı dozaj formülasyon sistemleri de dahil olmak üzere GEA tarafından ilaç endüstrisi için üretilen tüm ekipmana takılabilmektedir. Yıkama prosesinin otomasyonu, tekrarlanabilirliği sağlar, doğrulama imkanı verir ve hizmet dışı kalma süresini minimuma indirir.

Lighthouse Probe™ - çevrim içi ölçüm

Lighthouse Probe™ - çevrim içi ölçüm

Lighthouse Probe™ kimyasal ve farmasötik proseslerinin gerçek zamanlı izlenmesi için kullanılabilir ve herhangi bir zamanda proses-içi pencere temizliği, proses esnasında yeniden kalibrasyon, yıkama yuvası ve sızdırmazlık için tam CIP (temizlik) ve -çok zorlu koşullarda bile- net bir iç görüş sağlar.

PMA™ Yüksek Parçalayıcı İşleyici

PMA™ Yüksek Parçalayıcı İşleyici

PMA™ High Shear and PMA-Advanced™ Mixer and Granulator is a multipurpose processor that's equally suitable for the high speed dispersion of dry powders, aqueous or solvent granulations, effervescent production and melt pelletization for Pharma applications.

GEA Insights

GEA haber bültenine abone olarak GEA yeniliklerinden ve hikayelerinden haberdar olun.

Kaydolun

Size yardımcı olmak için buradayız! Sadece bir kaç detay ile sorgulamanıza yanıt verebileceğiz.

Bizimle irtibat kurun