Manufacturing Highly Potent Cytotoxic, Anticancer and Oncology Drugs
With an increasing emphasis on both operator safety and product protection, the commercial-scale production of oncology drugs, hormonal products and/or other highly potent compounds has been put under the pharmaceutical spotlight in recent years.
Eliminating the need for cumbersome isolation suits to prevent operators being exposed to hazardous substance and avoid cross-contamination with other products manufactured in the same facility, GEA’s approach is to use containment interfaces (the BUCK® MC high-containment range and disposable Hicoflex® products) to ensure compliance with global regulatory cGMP requirements.
Experts in contained material handling, closed product processing, gentle product treatment, the efficient recovery of active ingredients and reliable scale-up, we supply modules, components and fully integrated batch and continuous lines for the production of oncology drugs and other therapeutic agents that deliver increased yields and reduced cycle times.
From R&D-scale and standalone production equipment to contained production lines, we understand the absolute importance of preventing cross-contamination in the production area, protecting both people and products, and working within Real Daily Intake (RDI) and Acceptable Daily Intake (ADI) limits with up to occupational exposure band (OEB) 5 drugs.
GEA has a wealth of expertise and an unparalleled depth of experience in the field of containment. The company not only offers a comprehensive range of robust and compliant containment products, it also boasts unrivaled experience in identifying the most appropriate solution and a thorough understanding of containment risk analysis.
Productos y tecnologías
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Contained Materials Handling Systems
Contained Materials Handling solutions for Primary and Secondary Pharmaceuticals and Healthcare. With extensive experience within the generics sector, supply a wide range of technologies and equipment that improve and enhance the efficiency and performance of Oral Solid Dosage production.
Continuous Direct Compression Line
The ConsiGma® DC for direct compression is the latest expansion of GEA's continuous portfolio for cost effective, compact, high yield manufacturing systems. It offers a robust and flexible manufacturing method for a wide range of products.
Continuous Granulation Lines
Continuous Processing is becoming more and more important in the pharmaceutical industry. GEA takes the lead in introducing this innovative technology with ConsiGma® - continuous high-shear granulation and drying lines.
Continuous Processing Lines for Pharma
At GEA, we believe that continuous processing improves the quality of pharmaceutical end products: by focusing on quality during the whole product lifecycle, not just “tested in” quality; and by understanding the capability of your processes, managing sources of variability and decreasing any associated risks.
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GEA Insights
El avance que revolucionó el secado por atomización
En 1976, los ingenieros de NIRO respondieron a un reto competitivo replanteándose las posibilidades del secado por atomización. Su idea se materializó en la torre multietapa MSD. Cincuenta años después, ese mismo principio fundamental contribuye a transformar los líquidos en los productos en polvo que se utilizan en productos nutricionales esenciales y en medicamentos importantes en todo el mundo. Perfeccionada a lo largo de décadas de experiencia en ingeniería, conocimiento de las necesidades de los clientes y desarrollo continuo, la torre de atomización MSD es una historia de innovación con un impacto duradero.
Más allá de la máquina: cómo potenciar el rendimiento de la planta
El hecho de que una máquina sea eficiente no significa que la fábrica lo sea. La mejora real suele comenzar por ir más allá de los equipos individuales y comprender cómo los procesos, los sistemas energéticos y las decisiones operativas se influyen mutuamente. Se trata de un enfoque holístico diseñado para descubrir oportunidades que, de otro modo, podrían pasarse por alto.
Cómo una válvula transforma la manera de elaborar alimentos y bebidas
En las plantas de alimentación y bebidas, las válvulas suelen accionarse mediante aire comprimido. GEA Hydract® Actuation Technology mueve las válvulas mediante agua, en un circuito cerrado controlado digitalmente. El resultado es una válvula que puede mantenerse en su sitio con exactitud y regularse con precisión. Esto se traduce en un menor consumo energético y un mayor control.
