Inhalables and aerosols, no matter whether they are in liquid or solid form, must be delivered to the oral cavity or the greater respiratory system.
Inhalation is often the preferred drug delivery method for lung diseases, offering a number of advantages for both patients and medical professionals for the administration of vaccines and other biological drugs. Producing powders for inhalation is relatively straightforward on a small scale; but, it can be hard to replicate at a commercial level.
To facilitate the process, GEA has developed a highly specialized spray drying system that offers large-scale particle engineering capabilities. This makes it possible to accurately manipulate the aerodynamic size and flow properties of particles to produce fine, free-flowing powders for applications such as commercializing biological compounds including hormones, peptides and proteins that risk degradation if ingested.
When it comes to mixing and blending very fine powders, homogeneity and stability are key factors during the production of inhalable drugs. As such, GEA also offers production-scale mixing and blending solutions to produce inhalable products (dry powders and suspensions).
The TRV high-speed blender, a standalone PharmaConnect® module, is particularly suitable for the rapid batch blending of small quantities of APIs with base excipients. By combining the high surface area of the main impeller blade with the directional effects of the feeder blade, rapid, homogenous and stable blends can be produced in a reproducible manner.
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Contained Materials Handling solutions for Primary and Secondary Pharmaceuticals and Healthcare. With extensive experience within the generics sector, supply a wide range of technologies and equipment that improve and enhance the efficiency and performance of Oral Solid Dosage production.
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GEA es uno de los mayores proveedores mundiales de sistemas para los sectores alimentario, de bebidas y farmacéutico. Nuestra cartera incluye maquinaria y plantas, así como tecnología avanzada de procesos, componentes y servicios integrales. Utilizados en diversos sectores, mejoran la sostenibilidad y la eficiencia de los procesos de producción en todo el mundo.GEA cotiza en el MDAX alemán y en el índice STOXX® Europe 600, y también se encuentra entre las empresas que componen los índices DAX 50 ESG y MSCI Global Sustainability.
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