Solid Dosage
Oncology
With our comprehensive portfolio of oral solid dosage solutions, we can supply full process lines with containment interfaces for process steps from API and excipient dispensing, dry milling, powder collection and blending through to tableting and coating.
Manufacturing Highly Potent Cytotoxic, Anticancer and Oncology Drugs
With an increasing emphasis on both operator safety and product protection, the commercial-scale production of oncology drugs, hormonal products and/or other highly potent compounds has been put under the pharmaceutical spotlight in recent years.
Eliminating the need for cumbersome isolation suits to prevent operators being exposed to hazardous substance and avoid cross-contamination with other products manufactured in the same facility, GEA’s approach is to use containment interfaces (the BUCK® MC high-containment range and disposable Hicoflex® products) to ensure compliance with global regulatory cGMP requirements.
Experts in contained material handling, closed product processing, gentle product treatment, the efficient recovery of active ingredients and reliable scale-up, we supply modules, components and fully integrated batch and continuous lines for the production of oncology drugs and other therapeutic agents that deliver increased yields and reduced cycle times.
From R&D-scale and standalone production equipment to contained production lines, we understand the absolute importance of preventing cross-contamination in the production area, protecting both people and products, and working within Real Daily Intake (RDI) and Acceptable Daily Intake (ADI) limits with up to occupational exposure band (OEB) 5 drugs.
GEA has a wealth of expertise and an unparalleled depth of experience in the field of containment. The company not only offers a comprehensive range of robust and compliant containment products, it also boasts unrivaled experience in identifying the most appropriate solution and a thorough understanding of containment risk analysis.
Products & Technologies
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Analytical, in-line control & measurement devices
Combining process monitoring using online analyzers, together with solid process engineering principles and advanced process modelling techniques will enable processes to be actively controlled in order to compensate for input variations.
CIP/SIP Solutions
Innovative CIP concepts of GEA meet comprehensive high standards. Our experts guarantee product safety at every point of the process. Every upgrade is adapted to individual local conditions and customer requirements and leads to noticeable savings.
Contained Materials Handling Systems
Contained Materials Handling solutions for Primary and Secondary Pharmaceuticals and Healthcare. With extensive experience within the generics sector, supply a wide range of technologies and equipment that improve and enhance the efficiency and performance of Oral Solid Dosage production.
Continuous Direct Compression Line
The ConsiGma® DC for direct compression is the latest expansion of GEA's continuous portfolio for cost effective, compact, high yield manufacturing systems. It offers a robust and flexible manufacturing method for a wide range of products.
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GEA Insights
Smart, stylish, circular: polycotton recycling with Circ
Resource-efficient fashion has been a long-sought ambition amid the fashion industry’s considerable contributions to global carbon emissions. The need to close the loop by recycling textile fibers into virgin-like materials is higher than ever but seemed like a distant dream until now: Circ, GEA’s American customer and pioneer in the field of textile recycling, might be rewriting the future of the fashion industry.
New food tipping point
Alternative proteins are promising – yet still expensive to produce. The usual response is that scaling up will solve this issue. But what if the solution was really about getting better, not just bigger? From more efficient, high-yield processes to upcycling waste heat, engineers are reshaping how we grow food.
A safer way to produce cancer treatments
As anti-cancer drugs become more powerful and complex, GEA is redefining how to safely freeze-dry these life-saving treatments.
