A Continuous process is a process where raw materials are continuously fed into a system at the same time as finished product is continuously removed at the end of the process train. The raw materials are processed in very small quantities, compared to batch processes, and in a controlled manner, which allows the operator to have consistent control over the critical process parameters and therefore the critical product quality attributes.
At GEA, we believe that continuous processing improves the quality of pharmaceutical end products: by focusing on quality during the whole product lifecycle, not just “tested in” quality; and by understanding the capability of your processes, managing sources of variability and decreasing any associated risks.
Our solution for continuous drying and particle processing plants is ConsiGma®, a 6 sigma-inspired manufacturing platform, incorporating different technologies to produce oral solid dosage forms in a continuous, cost-efficient way:
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The ConsiGma® 1 offers standalone continuous twin-screw granulation and drying for small-scale R&D operations. It allows users to develop the process and achieve high granule quality on a compact unit.
An indispensable part of the ConsiGma portfolio, the Conductor control system architecture ensures smooth operation and communication between the different elements of a pharmaceutical continuous manufacturing line
A highly integrated solution for continuous linear blending and direct compression, the ConsiGma® DC-LB lines offer all the advantages of continuous manufacturing: supply chain agility, small footprint, controlled blending and compression and improved quality.
A cost-effective solution for continuous dry blending and tablet compression using ribbon blending, ConsiGma® DC-RB lines make the advantages of continuous manufacturing (supply chain agility, small footprint and improved quality) available for all.
The impact of global warming is increasingly apparent all over the world. Towns and cities everywhere face the same challenge: providing their communities with reliable, affordable, sustainably sourced heat. GEA spoke with an expert in the field, Kenneth Hoffmann, Manager, Heat Pumps at GEA Heating & Refrigeration Technologies, about tackling global warming faster.
Something caught Farmer Tom's eye. Instead of another product demo, GEA showcased innovations via AR. That's only the start of GEA's interactive digital farm.
GEA scientists are working with researchers at the Graz University of Technology to configure a homogenization process and technology that turns eucalyptus pulp into 3D-printed, organic structures mimicking human veins, arteries and other tissues.