Cleaning-in-Place for Pharma Applications
CIP for Pharmaceutical Process Plants
Clean-in-Place (CIP) and Sterilize-in-Place (SIP) systems are designed to both automate essential cleaning and disinfection processes and remove the need for time-consuming disassembly and assembly work.
Compliant Cleaning Solutions and Cost Benefits
The most effective way to implement CIP technology is to design it into a process. Incorporating spray systems, tank cleaners, nozzles and seals to automate the cleaning process, we at GEA consider every aspect of your system when applying CIP features, from inlet to discharge.
Automating the cleaning cycle essentially converts batch pharmaceutical processes into a continuous operation of production and cleaning cycles. The advantages of CIP include
- reduced cleaning cycle times
- optimized use of detergent and water
- eliminates manual cleaning.
At the heart of our CIP system is an advanced Wash Liquid Preparation Unit, which handles all filtering, preheating, mixing and pumping of water, detergents and demineralized water. It provides continuous monitoring and control of cleaning parameters, including flow rate, detergent concentration, temperature and wash time for full process validation.
CIP/WIP System Skids
In today's pharmaceutical processes, integrated CIP solutions play a key role: from system skid selection to identifying the intended targets and required parameters. Variables such as temperature, velocity/pressure, chemical concentration and exposure time can all be controlled using a programmable GEA CIP skid to deliver reliable, repeatable and verifiable results.
Our CIP/WIP system skids are designed, engineered, fabricated, automated and tested in-house. This vertically integrated approach allows for open communication between disciplines, enabling rapid response times to any variances that occur during the project lifecycle. A qualified Project/Process Engineer is assigned to your project to facilitate discussions regarding site-specific requirements, integration concerns and final FAT protocols.
In addition to defining and configuring your system skid, GEA can further assist you to integrate CIP into your hygienic process and plant, ranging from conventional "make/break" manual flow panel methodology to the latest in matrix piping technology that utilizes mix-proof valve systems.
GEA's CIP units are designed to guarantee successful cleaning and reduced waste generation. They can be integrated for the single use recovery of cleaning media, for single or multi-stream routes as well as for online and offline cleaning and sanitization. Our units provide functionality for CIP/SIP configurable recipes for water rinses, chemical washes, blow down and air drying, sanitation (heat or chemical), and flow, pressure, concentration and temperature controls
Combined with our GEA VARIVENT® valves and spray jets ranges, our CIP systems provide a safe solution for product and cleaning efficiency. GEA also offers wash systems for mobile tanks and IBCs.
Downloads
GEA Insights
Using everything: How by-product processing reduces food waste
Maximizing the value of every resource is key to a circular economy. Modern technology unlocks the vast potential in animal by-products, transforming side-streams into valuable proteins, fats and biofuels for new, more sustainable value chains.
Arla cuts spray dryer CO₂ with GEA AddCool® system
GEA AddCool® installation cuts CO2 emissions associated with the operation of a spray dryer plant by 1,500 tons per year at Arla’s milk powder factory in Svenstrup, Denmark.
A headquarters with people and purpose at its core
GEA’s new corporate headquarters in the up-and-coming Derendorf neighborhood of Düsseldorf, Germany, brings together people, ideas and expertise under one roof. With its open spaces, green terraces and energy-efficient design, the building reflects the company’s commitment to collaboration and sustainability.
