ConsiGma®
ConsiGma® Direct Compression with Ribbon Blending (DC-RB) Lines
A cost-effective solution for continuous dry blending and tablet compression using ribbon blending, ConsiGma® DC-RB lines make the advantages of continuous manufacturing (supply chain agility, small footprint and improved quality) available for all.
Available in 3 standard sizes, depending on the desired throughput (from 10 to 200 kg/h or 20,000 to 400,000 tablets/h, to be verified by testing), the systems can be customized with a number of options to suit customer needs.
The Conductor 4.0 software ensures seamless control of the entire process and full reporting. Tracking of OOS and material genealogy can be integrated into the controls.
Mainly targeted towards generics, nutraceuticals, OTC production and CMOs, the systems are designed to handle easy-to-blend and high-throughput DC formulations.
Standard Configuration
- 2 to 4 loss-in-weight feeders
- 1 ribbon blender
- GEA compression system
Available Options
- Choice of feeder (GEA or qualified third-party supplier)
- Set-up of blender: continuous flow or mini-batch
- Blend uniformity measurement with Lighthouse Probe®
- Material handling system including containment features
Main Benefits
- Flexible batch size
- Small footprint
- Eliminate work in progress
- Adaptable to blending of even fragile particles such as MUPS
- Higher blend homogeneity – all powder particles go through the same mixing event
- Higher material yield
- High flexibility from very low to very high API content
- In-process blend uniformity control – second-by-second
- Adaption to variable throughput capacities
- No hold-up issues
Read more about how GEA and its partners are implementing this technology to lead the way toward smaller, more flexible, continuous processing technologies that are transforming the future of pharmaceutical development and manufacturing.
Downloads
Verwandte Produkte
ConsiGma® Direct Compression with Linear Blending (DC-LB) Lines
A highly integrated solution for continuous linear blending and direct compression, the ConsiGma® DC-LB lines offer all the advantages of continuous manufacturing: supply chain agility, small footprint, controlled blending and compression and improved quality.
ConsiGma® Tablet Coating (TC) Modules
The ConsiGma® TC modules are based on the GEA high-performance tablet coating technology that gently and accurately deposits controlled amounts of coating materials onto tablet cores — even if they are hygroscopic or friable.
Lighthouse Probe® - online measurement
The Lighthouse Probe® can be used for real-time monitoring of chemical and pharmaceutical processes and provides in-process window cleaning at any time, recalibration during the process, full CIP (cleaning) of wash housing and seal, and a clear view inside – even in difficult conditions.
ConsiGma® 1 - R&D Granulation and Drying
The ConsiGma® 1 offers standalone continuous twin-screw granulation and drying for small-scale R&D operations. It allows users to develop the process and achieve high granule quality on a compact unit.
GEA Insights
Modernes Herdenmanagement: Eine klügere Art zu wirtschaften
In einer Milchviehherde hat jede Kuh ihre eigene Geschichte - und moderne Herdenmanagement-Tools helfen, diese zu erzählen. Durch die Erfassung von Indikatoren zum Gesundheitsstatus, zum Tierverhalten und Leistungsstand ermöglichen diese intelligenten Systeme den Landwirten, die Tiere optimal zu versorgen, die Herde effizienter zu managen und hochwertige Milch zu produzieren. Das ist das Geheimnis vitaler Herden und erfolgreicher, nachhaltiger Milchviehhaltung.
Lebensmittel für die Zukunft: Die Power der Gefriertrocknung
Die Vermeidung von Verschwendung ist uns bei GEA wichtig, und durch die Nutzung der Leistungsfähigkeit der Gefriertrocknungstechnologie können wir überschüssige Nahrungsmittel in wertvolle, haltbare Produkte umwandeln – und so dazu beitragen, Abfallmengen zu reduzieren, die Lagerfähigkeit zu verlängern und eine nachhaltigere Lebensmittelversorgung für künftige Generationen zu schaffen.
