Coating is an important unit operation used to either modify color, give protection, for taste masking or to create a modified release form in pharmaceutical production. GEA is able to offer some novel as well as all typically used coater systems for particles, powders, granules, crystals, pellets and tablets.
NexGen Press® 30 with integrated ConsiGma® coater
GEA is an established supplier of coater systems for particles, powders, granules, crystals, pellets and tablets and is able to provide equipment for many of the typically used coating technologies and assist with the selection of the process that best suits your needs.
Coating is an important unit operation that’s used extensively in the pharmaceutical industry for the application of non-functional or functional coats (aesthetic, protective or rate controlling polymer films) and for the deposition of active pharmaceutical ingredients (APIs) onto nonpareils (multi-particulate dosage forms). Applications include taste masking, color modification, physical protection and/or to create modified release forms.
Beyond efficient API layering techniques for multi-particulate systems, the pharmaceutical industry has an inherent need to accurately coat objects that are 3–30 mm in length (the most common size range for single-unit solid dosage forms) with APIs. These include tablets for oral administration and other delivery methods (human implantation, for example). Existing coating methods in this size range have coating speed and accuracy/uniformity limitations, particularly for the deposition of low dose APIs onto single unit tablet dosage forms.
Available technologies include fluid bed coating for smaller particles, such as powders, granules, seeds, crystals, pellets, and small tablets, a multipurpose processor that uses proven fluid bed technology to achieve granulation, drying and pellet coating (or tablet coating) in a single processor and a revolutionary tablet coater that accurately deposits controlled amounts of coating materials on tablets, even if they are hygroscopic or friable.
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Committed to providing flexible, modular equipment to support research and development in the pharmaceutical industry, the multipurpose AirConnect from GEA delivers a range of fluid bed processing solutions for small-scale applications.
FlexStream is a multi-purpose processor that addresses the shortfalls of traditional fluid bed processing, including linear scale-up, fully contained loading and unloading for Pharmaceutical applications.
GEA has expanded its popular PharmaConnect® system with the introduction of PharmaConnect®-PLUS, extending the unit’s high shear granulation capacity to encompass batch sizes of up to 60 kg.
特定用途向けの研究開発のために幅広い技術を提供する当社の小規模装置シリーズは、経口固体製剤生産のあらゆる側面を網羅しており、高剪断力混合機、流動床乾燥機およびシングルポットシステムから押し出し機およびスフェロナイザ、ブレンダおよび封じ込めソリューション、錠剤圧縮に至るまで、幅広い装置を対象にします。
ConsiGma Coater - real-time video of coating cycle
With the GEA kytero 10, researchers and developers in the biopharmaceutical, food and new food industries now have the latest generation of a powerful accelerator at their disposal.