Liquid Dosage
Antibiotics
Antibiotics, compounds or substances that combat bacterial infections and kill or slow down their growth, comprise one of the most important groups of drugs in the fight against infectious diseases. Representing around 13% of total pharmaceutical consumption, they have the highest market share of any pharmaceutical product.
In liquid-based applications, the pharmaceutical industry extracts antibiotics from fermentation broths. GEA supports this process with special decanters that facilitate the process, offering efficient direct extraction solutions that are also environmentally friendly.
The Extraction Process
Extraction essentially consists of two combined processes: mixing and separating. GEA has developed a patented decanter that combines the two process steps in a single machine to enhance the extraction of active ingredients.
This decanter allows suspensions with a high solids content to be processed, rendering them suitable for direct antibiotic extraction from the culture solution (which often has a high mycelium content). The previously essential filtration step is no longer required, which not only makes the process continuous, it also prevents the loss of valuable material that was frequently associated with filtration.
Advantages of Direct Extraction
Offering increased total yields of up to 98% compared with conventional counter-current extraction, direct extraction is also significantly more cost-effective (no filter aids are needed). The fermentation broth itself is not diluted by filter wash water, which both reduces the solvent requirement and the risk of infection. In addition, the optimized procedure also reduces wastewater pollution and the actual volume of wastewater produced.
The GEA Solution
Driven by new product innovations, high levels of R&D investment and the pharmaceutical industry’s need to ameliorate the issue of antibiotic resistance, the antibiotic market is expected to show continued growth. From R&D-scale and standalone manufacturing equipment to completely integrated process lines that maximize operational reliability, GEA supplies a complete range of equipment and solutions for the industrial-scale production of antibiotics, antibacterials and anti-infectives.
製品および技術
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CIP/SIP ソリューション
GEA の革新的な CIP コンセプトは、包括的な最高規格を満たしています。当社のエキスパートは、プロセスのあらゆる時点で、製品の安全性を保証しています。どのアップグレードも、現場の個々の条件および顧客の要件に適合し、顕著な節約を実現します。
GEA Varipump
The pump models in the GEA Varipump line are conceived for extreme application demands and are individually optimized for your task.
Hygienic pumps
GEA Hilgeでは、飲料、食品、製薬産業における多岐にわたる感度の高い用途に汎用性の高い遠心ポンプおよび容積型ポンプをご用意しております。
Industrial spray dryers
Our fully customizable and highly reliable spray dryers deliver quality powders that enable you to meet your customers’ needs today and tomorrow.
GEAインサイト
食卓に登場するニューフードが食の未来を創造
コーヒー、カカオ、牛乳、肉、魚、卵。こういった毎日の定番ともいえる食材は、集約農業に大きく依存しています。ニューフード技術の台頭に伴い、これまで以上に持続可能な代替食品を使用できるようになりました。そこで今回は、GEA で液体・発酵・充填担当上級副社長を務めるライマー・グッテ博士と対談し、その可能性と政策について探ってみました。
Innovating patient care with aseptic spray drying
At GEA, our commitment to engineering for a better world fuels our pursuit of innovative solutions that enhance patient care and safety. One of our most promising ventures in recent years is aseptic spray drying – a technology...
レシチンが単なる副産物から主役に変貌を遂げるまで
GEA製品販売部長のパトリック・シュールマンにとって、レシチンは特別な存在です。当初は食用油の精製において脇役にすぎなかったものの、何にでも使える物質として、競争が激しく利益率の低い食用油精製市場で見事に主役の座を獲得。実はこれ、シュールマンが同僚と一緒に開発した、革新的で省エネな新製法によるところが大きいのです。
