ConsiGma®
ConsiGma® 1 - R&D Granulation and Drying
Based on proven continuous twin-screw granulation technology, the ConsiGma® 1 has been designed for the small-scale development of continuous granulation processes.
The system comprises the same twin-screw granulator as the smallest unit of the ConsiGma® CTL lines and a small dryer that’s similar to one of the drying segments. This allows you to develop your products on the same scale with product quantities starting from just a few 100 grams up to a few kilograms. The results are directly transferrable to the standard size ConsiGma® CTL.
The ConsiGma® 1 is ideal for pharmaceutical companies who wish to develop a continuous granulation process before the fully integrated production line is installed.
Standard Configuration
- One powder feeder
- One liquid addition system
- Twin-screw granulator
- One dryer segment
Available Options
- Brabender or Ktron Feeder
- Standalone ConsiGma® 1 w/out dryer segment
- Solvent-compatible
- Second liquid addition
- Lighthouse Probe® for LOD measurement
- Melt granulation set-up
Main Benefits
- Controlled granulation
- Less API use during R&D
- Fast R&D
- Reduced time-to-market
- No scale-up from ConsiGma® 1 to ConsiGma® CTL 25
Read more about how GEA and its partners are implementing this technology to lead the way toward smaller, more flexible, continuous processing technologies that are transforming the future of pharmaceutical development and manufacturing.
Downloads
Verwandte Produkte
ConsiGma® Film Coater
The ConsiGma® Film Coater is based on the GEA high-performance tablet coating technology that gently and accurately deposits controlled amounts of coating materials onto tablet cores — even if they are hygroscopic or friable.
ConsiGma® Direct Compression with Linear Blending (DC-LB) Lines
A highly integrated solution for continuous linear blending and direct compression, the ConsiGma® DC-LB lines offer all the advantages of continuous manufacturing: supply chain agility, small footprint, controlled blending and compression and improved quality.
ConsiGma® Granulation and Compression (GC) Lines
Highly integrated solutions for continuous wet granulation, drying and tablet compression, the ConsiGma® GC lines offer all the advantages of continuous manufacturing: supply chain agility, small footprint, controlled granulation and improved quality.
Lighthouse Probe® - online measurement
The Lighthouse Probe® can be used for real-time monitoring of chemical and pharmaceutical processes and provides in-process window cleaning at any time, recalibration during the process, full CIP (cleaning) of wash housing and seal, and a clear view inside – even in difficult conditions.
GEA Insights
Veränderungen bei Lebensmittelverpackungen: 4 Trends
Das Thermoformen ist ein seit langem etablierter Prozess in der Lebensmittelverpackung. Nun steht es vor einem tiefgreifenden Wandel. Angesichts strengerer Vorschriften, sich weiterentwickelnder Materialien und steigender Kosten müssen Form-Fill-Seal-Anlagen mehr leisten als nur zuverlässig zu laufen – sie bestimmen maßgeblich, wie Lebensmittel frisch, erschwinglich und recycelbar bleiben. Wir geben Ihnen einen Überblick über die wichtigsten Trends im Thermoformen, die die Landschaft der Lebensmittelverpackung und -lieferung prägen.
Obstlagerung bei Betko: Kontrolle vom Erntehöhepunkt bis zur weltweiten Auslieferung
Von den Obstplantagen am Kap bis in die Regale von 40 Ländern – das südafrikanische Verpackungsunternehmen Betko hat sein Geschäft auf Frische, zeitliche Präzision und Zuverlässigkeit aufgebaut. Dank der Kühltechnologie mit kontrollierter Atmosphäre von GEA kann das Unternehmen nun Äpfel und Birnen bis zu 14 Monate lang lagern und den Energieverbrauch um 20 % senken. All dies basiert auf einer mehr als 30-jährigen Partnerschaft.
