Liquid Dosage
Therapeutical Proteins
Protein-based therapeutics are increasingly being developed as new chemical entities in the pharmaceutical and life science industries. Unlike small molecules, which are typically synthesized using chemical processes, most proteins need to be processed in living systems, mostly by recombinant DNA technology. The proteins can then be produced in their functional form (quaternary structure), rather than by microbial biosynthesis (bacteria/yeast), substantially reducing the downstream stages of the process.
The GEA Advantage
As the demand for large-volume products increases, so does the requirement for higher capacity reactors (up to 20,000 L) to realize economies of scale. GEA has responded to the changing needs of biopharmaceutical manufacturers and developed improved technology solutions to optimize both upstream and, with increasing titers, downstream processing, in terms of time and cost efficiency.
Based on its history of innovation and process development, GEA has a thorough working knowledge of therapeutic protein production and has used this competence to design better media and feeding strategies, optimize the fermentation stage and enhance physicochemical conditions during the manufacturing process.
A leading international supplier of integrated process systems, our extensive portfolio of products, technologies and services includes standard and customized fermenters, separators and entire production lines, as well as plant for the production, storage and distribution of clean utilities. Systems for the preparation of media, fluid management, cell cultivation and purification are also part of our global scope of supply.
As a competent manufacturer of complete plant for the life science industries, GEA is a full-service provider of solutions that meet your exact requirements and specifications. From planning, development and installation to qualification and maintenance, our experienced engineers will collaborate with your project team to supply innovative and efficient process solutions for your applications.
Produtos e Tecnologias
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Bloco de compressão homogeneizador
As cabeças de compressão da GEA são o centro pulsante do homogeneizador, pois podem ativar o processo de homogeneização, bombeando o produto em alta pressão até que ele flua dentro da válvula de homogeneização.
Clarificador
Centrífugas clarificadoras são usadas para separar sólidos dos líquidos. A centrífuga é equipada com um jogo de pratos cônicos para a criação de uma grande área de clarificação equivalente em um volume de tambor relativamente pequeno.
Dispositivos analíticos, de controle em linha e de medição
Combinar o processo de monitoramento usando analisadores on-line, juntamente com princípios de engenharia de processo sólidos e técnicas de modelização de processo avançadas permitirá que os processos sejam ativamente controlados de modo a compensar as variações de entrada.
GEA Varipump
The pump models in the GEA Varipump line are conceived for extreme application demands and are individually optimized for your task.
Insights da GEA
Preparando a cadeia frigorífica para o futuro com refrigeração sustentável
A importância do gerenciamento de qualidade da cadeia frigorífica não pode ser subestimada. Garantir que os gêneros alimentícios perecíveis sejam seguros e de alta qualidade no ponto de consumo é uma enorme responsabilidade para...
