Understanding R&D Continuous Processing – Hands-on Workshop

During our Understanding R&D Continuous Processing workshops, we will focus on optimizing particle size distribution using different screw elements, melt granulation with a twin screw granulator and conducting a design of experiment (DoE) test with a minimal amount of product. 

We will also investigate process transfer from the laboratory scale ConsiGma^® 1 to the production-size ConsiGma^® 25 as a case study.

On completing the training, participants will benefit from a thorough understanding of pharmaceutical continuous processing technology, be able to set up a DoE for continuous granulation and have developed a much better awareness of continuous manufacturing terminology. Furthermore, they will have gained hands-on continuous granulation and drying experience, and recognize how to improve operational performance and optimize a product.

The workshops are designed to be fully interactive, and each participant will have the opportunity to ask questions and share real-life experiences. All presentations and demonstrations will be given by our experienced process specialists.

The workshops are aimed at R&D scientists and managers, production supervisors, quality assurance staff, process engineers and trainers.

9h00 – 10h00 

Introduction to Continuous Granulation and ConsiGma® 1

10h00 – 10h30 

Explanation of DoE principles and how to apply to continuous granulation

10h45 – 12h15 

Demonstration: Granulation of a placebo formulation showing:

• optimization of particle size distribution by modifying screw configuration
• LHP PAT moisture measurement
• Starting DoE experiments

13h15 – 14h45 

Continuation of DoE practical work

15h00 – 16h30 

Scale-up demonstration from ConsiGma®-1 to production equipment (ConsiGma®-25 continuous tableting line)

9h00 – 9h30 

Melt granulation on a continuous granulator

9h30 – 11h00 

Demonstration of melt granulation

11h15 – 12h15 

PAT in continuous processing

Registration fee: 750 EURO per person

The registration fee to the workshop covers the following items:

• participation in the lectures & demonstrations for 2 days
• information binder with all presentations
• lunch on all workshop days
• dinner after the first workshop day
• Travel and hotel expenses are not included.

Registration will only become effective upon receipt of payment.

Payment information will be supplied after the registration form has been received.