Lyophilization Technology SMART LYO™ Pharma Freeze Dryer

SMART LYO™ Freeze Dryers help reduce the cost of freeze drying while maintaining quality and performance, making validation and documentation easier and reducing delivery times.

SMART LYO™ Freeze Dryers

SMART LYO™ pharmaceutical lyophilizers are made from proven standardised modules to keep costs down and quality up. They are available in shelf sizes of 0.4 m² up to 41.2 m² with a condenser capacity of up to 800kg, suitable for most applications. Using already proven technology shortens delivery time and validation periods, and enables customers to bring their products to market more quickly. They meet the highest possible technical requirements, the strictest standards of the global licensing authorities, and comply with all the current guidelines such as GAMP, cGMP, FDA etc.

SMART LYO™ SL 10 - 80 for Research and Development

Lyophil_SMART_LYO_SL_60

These small-scale lyophilizers are available in shelf size of 0.4 - 8 m². The pilot plant is ideal to prove and scale-up for GEA’s larger industrial-size freeze dryers, and complete freeze dryer systems, which feature automatic loading and unloading systems (ALUS™). They are used for the following applications: Product development and process cycle optimization, Up Scaling of the process for later use in Production Plants and Small Scale production especially for Biotech customers.

ModelUnitsSL 10SL 20SL 40SL 60SL 80
Shelves
Shelf area0,6 / 0,71,1 / 1,41,9 / 2,22,8 / 3,34,2 / 5
No. of Vials (Ø 16mm)Quantity3.0806.0209.67814.62822.038
No. of vials (Ø 22mm)Quantity1.600   3.1005.0227.61411.562
No. of vials (Ø 30mm)Quantity8001.6702.6944.0986.198
No. of shelvesQuantity4 / 5 + 14 / 5 + 15 / 6 + 15 / 6 + 15 / 6 + 1
Shelf sizemm460 x 310460 x 610610 x 610610 x 914914 x 914
Clearancemm120 / 90120 / 90120 / 100120 / 100130 / 110
Shelf temperature-55 ... +70-55 ... +70-55 ... +70-55 ... +70-55 ... +70
Condenser
Condenser capacitykg/24h1020406080
Condenser temperature-75-75-75-75-75
Unit dimension
Length (B)mm2.6002.8003.5004.0004.200
Width (A)mm1.4001.4002.1002.3002.300
Hightmm2.4002.4002.4002.4002.400
Weights
Unitt23,54,567,5
 

SMART Features

  • The entire system is constructed on a single-floor plant frame for fast, simple commissioning
  • The system includes: the compact chamber/condenser unit, all system modules (hydraulics, venting system, vacuum) and available options such as CIP and SIP, interfacing to ALUS™ (Automatic Load/Unload System) 
  • Refrigeration unit can be installed remotely from the plant frame, on a different floor if necessary, enabling the installation to be adapted to fit the customer’s infrastructure
  • Electrical cabinet can be positioned in the freeze dryer plant or centrally in a control room 
  • Frame mounting allows SMART LYO™ freeze dryers to be installed in the existing building architecture (the machinery room and the sterile area); installation and assembly is, therefore, very simple, only requiring the plant to be connected to the unit frame and the switch cabinet 
  • GEA Global Service Network provides rapid worldwide access to original spare parts and a comprehensive repair service that minimizes downtime and keeps costs under control.

SMART LYO™ Production Scale Freeze Dryers SL 100 - SL 800

Lyophil_SMART_LYO_Integrated_FAT

The entire system is constructed on a single-floor plant frame for fast, simple commissioning. The system includes: the compact chamber/condenser unit, all system modules (hydraulics, venting system, vacuum) and available options such as CIP and SIP, interfacing to ALUS™ (Automatic Load/Unload System)  

ModelUnitsSL 100SL 200SL 300SL 400SL 600SL 800
Shelves
Shelf area6,71014,920,430,241,2
No. of vials (Ø 16mm)Quantity29.49644.24465.69090.530133.913182.865
No. of vials (Ø 22mm)Quantity15.49823.24734.34047.36070.35696.585
No. of vials (Ø 30mm)Quantity8.14212.21318.40025.52037.70051.750
No. of shelvesQuantity6 + 19 + 110 + 111 + 113 + 115 + 1
Shelf sizemm914 x 1219914 x 12191219 x 12191219 x 15241524 x 15241524 x 1803
Clearancemm120120120120120120
Shelf temperature°C-55 ... +70-55 ... +70-55 ... +70-55 ... +70-55 ... +70-55 ... +70
Condenser
Condenser capacitykg/24h100200300400600800
Condenser temperature°C-75-75-75-75-75-75
Unit dimensions
Length (B)mm5000560060006500Depending on Layout
Width (A)mm3000300034003400
Heightmm3500400042004300
Weights
Unitt7,5912,51517,519