There are few things that all human beings share – but blood is one of them. Everyone has it and without it we die. But what is it? What does it do? And why is it the basis of a global industry?
First some facts. The average adult body contains around five liters of blood, which accounts for around eight per cent of body weight. Whole blood is a suspension of cells in a liquid called blood plasma. Plasma accounts for 55 per cent of the volume of blood and is itself 91 per cent water, in which are dissolved various proteins and a whole host of essential trace elements from hormones and neurotransmitters to amino acids and vitamins. Plasma circulates nutrients around the body and removes waste products such as carbon dioxide.
The other 45 per cent of blood volume consists overwhelmingly of red blood cells, together with a small proportion of white blood cells and platelets. These are all produced in the body’s bone marrow. Red blood cells, which give human blood its color, distribute oxygen and nutrients around the body. White blood cells are part of the immune system and platelets are responsible for blood clotting.
Blood keeps people alive: and even before the development of scientific medicine, doctors knew that it was vital. The practice of bloodletting – deliberately cutting the patient to allow a quantity of blood to flow out – was one of the commonest medical procedures from the ancient world to the 19th century and was used to treat virtually any disease.
GEA and blood
The processing of blood must meet highest requirements to ensure clinical excellence. GEA Process Engineering company GEA Diessel is a specialist in this field using its experience and expertise to unite vital GEA technologies to create complete processing plants for blood and plasma processing: centrifugation, nano-filtration, chromatography and precise temperature control. The company has successfully planned and built plants for plasma fractionation in Germany, Switzerland and China.
Depending on the application, plasma needs to be frozen to -30°C within 60 minutes. GEA Heat Exchangers provides variants of GEA Küba’s SG air coolers which can accurately maintain such extreme low temperatures.
GEA Westfalia Separator Group, part of GEA Mechanical Equipment, is at the forefront of developments in processing blood plasma. Thanks to a unique design feature the Westfalia Separator® hycon now allows the discharge process to be fully automatic. This saves time and makes the process safer for the product and operator. The suitability of the separator for CIP and SIP processes guarantees sterile handling of the blood plasma protein during the entire fractionation process. All hycon components coming into contact with the product can be cooled – essential for human blood plasma fractionation. Also production can be carried out at room temperature, rather than the entire production area being at -5°C.